SCHEMBL2875216

SCHEMBL2875216

ClC(Cl)CCCc1ccc(CCCC(Cl)Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
FDFT1 P37268 2/20 0.37
MAOB P27338 2/20 0.36
HTR2A P28223 2/20 0.36
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
IGF1R P08069 1/20 0.34
ALOX15 P16050 1/20 0.34
ESR1 P03372 2/20 0.33
ADRA2A P08913 2/20 0.33
ADORA3 P0DMS8 2/20 0.33
TACR2 P21452 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
GFER P55789 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2880972 0.92 MAOB (0.39) MAOBHTR2AALDH1A1HSD17B10HPGD
SCHEMBL2408105 0.87 SIGMAR1 (0.48) MAOBHTR2ASLC6A3
SCHEMBL2878724 0.82 GFER (0.36) FDFT1ESR1GFERKDM4E
SCHEMBL9503365 0.82 MAOB (0.33) MAOBHTR2AALDH1A1HSD17B10IGF1R
SCHEMBL6681949 0.80 MAOA (0.52) MAOB
SCHEMBL6633971 0.80 IGF1R (0.47) FDFT1HTR2AALDH1A1HSD17B10IGF1R
SCHEMBL9549434 0.80 IGF1R (0.47) FDFT1HTR2AALDH1A1HSD17B10IGF1R
SCHEMBL6682926 0.79 SIGMAR1 (0.52) MAOB
SCHEMBL6682661 0.79 SIGMAR1 (0.52) MAOB
SCHEMBL6684932 0.79 SIGMAR1 (0.52) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100151392-A1 ANTIREFLECTIVE COATING COMPOSITIONS RAHMAN M DALIL 2010-06-17 US disclosed
US-5387672-A For use in oxygen-transporting fluids THE UNIVERSITY OF MARYLAND AT BALTIMORE (US) 1995-02-07 US disclosed