Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | IGF1R | P08069 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880972 | 0.89 | MAOB (0.39) | MAOBIGF1RALOX15ALDH1A1ESR1 | |
| SCHEMBL2875216 | 0.82 | PPARG (0.38) | MAOBIGF1RALOX15ALDH1A1ESR1 | |
| SCHEMBL6681949 | 0.78 | MAOA (0.52) | MAOBMAOATRPA1 | |
| SCHEMBL28477169 | 0.78 | FUT7 (0.41) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL6633971 | 0.78 | IGF1R (0.47) | IGF1RALOX15ALDH1A1ESR1ADRA2A | |
| SCHEMBL9549434 | 0.78 | IGF1R (0.47) | IGF1RALOX15ALDH1A1ESR1ADRA2A | |
| SCHEMBL6682661 | 0.77 | SIGMAR1 (0.52) | MAOBMAOATRPA1 | |
| SCHEMBL6682926 | 0.77 | SIGMAR1 (0.52) | MAOBMAOATRPA1 | |
| SCHEMBL6684932 | 0.77 | SIGMAR1 (0.52) | MAOBMAOATRPA1 | |
| SCHEMBL9195603 | 0.74 | THRA (0.38) | MAOBIGF1RALOX15ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273444-B1 | USE OF CARBOXAMIDE COMPOUNDS FOR THE PREPARATION OF A MEDICAMENT FOR TREATING HYPERLIPIDEMIA | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1993-05-05 | — | — | EP | disclosed |