Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
| ▸ | GSK3A | P49840 | 2/20 | 0.60 |
| ▸ | GSK3B | P49841 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6345642 | 0.82 | MGLL (0.57) | MGLLFAAHGSK3AGSK3BCTRB1 | |
| SCHEMBL2569297 | 0.80 | PABPC1 (0.60) | CTRB1KMT2ACYP1A2 | |
| SCHEMBL13943755 | 0.80 | KMT2A (0.53) | CTRB1DAOKMT2ACYP1A2CYP2A6 | |
| SCHEMBL140975 | 0.78 | MGLL (0.72) | MGLLFAAHGSK3AGSK3BKMT2A | |
| SCHEMBL146412 | 0.77 | MGLL (1.00) | MGLLFAAHGSK3AGSK3BHSP90AA1 | |
| SCHEMBL14740673 | 0.77 | CES1 (0.68) | CTRB1CYP1A2ACHE | |
| SCHEMBL25435490 | 0.76 | MGLL (1.00) | MGLLFAAHGSK3AGSK3BKMT2A | |
| SCHEMBL207740 | 0.76 | MGLL (1.00) | MGLLFAAHGSK3AGSK3BKMT2A | |
| SCHEMBL8079266 | 0.75 | GSK3A (0.66) | GSK3AGSK3BCTRB1DAOKMT2A | |
| SCHEMBL29702290 | 0.74 | GSK3A (0.67) | GSK3AGSK3BCTRB1DAOKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114432301-B | Covalent inhibitor derivative and application thereof in treatment of viral infection | 北京大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-114432301-A | Covalent inhibitor derivative and application thereof in treating virus infection | 北京大学 | 2022-05-06 | — | — | CN | disclosed |