Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13437657 | 0.91 | P2RY1 (0.71) | P2RY1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL2880008 | 0.90 | P2RY1 (0.69) | P2RY1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL13019011 | 0.89 | NPC1 (0.61) | P2RY1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL13063448 | 0.88 | P2RY1 (0.61) | P2RY1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL13078478 | 0.87 | P2RY1 (0.60) | P2RY1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL2877205 | 0.87 | P2RY1 (0.69) | P2RY1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL2878288 | 0.84 | P2RY1 (1.00) | P2RY1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL13019012 | 0.84 | P2RY1 (0.62) | P2RY1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL11724397 | 0.82 | PARP14 (0.55) | P2RY1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL11726409 | 0.82 | P2RY1 (0.56) | P2RY1RAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899299-B1 | C-LINKED CYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB CO (US) | 2010-10-20 | — | — | EP | disclosed |
| EP-1899299-B1 | C-LINKED CYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB CO (US) | 2010-10-20 | — | — | EP | disclosed |
| US-7700620-B2 | C-linked cyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-04-20 | — | — | US | disclosed |
| US-7700620-B2 | C-linked cyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-04-20 | — | — | US | disclosed |
| US-7700620-B2 | C-linked cyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-04-20 | — | — | US | disclosed |
| EP-1998746-A2 | LIPOPHILIC PERSONAL CARE COMPOSITION | The Procter & Gamble (US) | 2008-12-10 | — | — | EP | disclosed |
| EP-1901812-A1 | LIPOPHILIC PERSONAL CARE COMPOSITION | The Procter and Gamble Company (US) | 2008-03-26 | — | — | EP | disclosed |
| EP-1899299-A2 | C-LINKED CYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | Brystol-Myers Squibb Company (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007102125-A2 | LIPOPHILIC PERSONAL CARE COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2007-09-13 | — | — | WO | disclosed |
| US-20070207103-A1 | Lipophilic personal care composition | THE PROCTER & GAMBLE COMPANY | 2007-09-06 | — | — | US | disclosed |
| WO-2007007250-A1 | LIPOPHILIC PERSONAL CARE COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2007-01-18 | — | — | WO | disclosed |
| US-20070009457-A1 | Lipophilic personal care composition | THE PROCTER & GAMBLE COMPANY | 2007-01-11 | — | — | US | disclosed |
| WO-2007002635-A2 | C-LINKED CYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060293336-A1 | C-linked cyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070207103-A1 | Lipophilic personal care composition | CUTA, PLIN3, PLIN5 | P2RY1 1504/4885RAB9A 4543/4885NPC1 563/4885 |
| US-20060293336-A1 | C-linked cyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | P2RY11, P2RY1, P2RY13 | P2RY1 2/4885RAB9A 3132/4885NPC1 3676/4885 |
| US-20070009457-A1 | Lipophilic personal care composition | HACD3, LIPA, PLOD3 | P2RY1 4610/4885RAB9A 4169/4885NPC1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.