Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | S100A4 | P26447 | 3/20 | 0.42 |
| ▸ | CDC25B | P30305 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6288350 | 0.73 | S100A4 (0.49) | TDP1S100A4CDC25BKMT2ATDP2 | |
| SCHEMBL27616642 | 0.72 | TDP2 (0.46) | TDP1S100A4CDC25BKMT2ATDP2 | |
| SCHEMBL28091316 | 0.70 | MEN1 (0.38) | MAPTKMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL16098756 | 0.68 | LMNA (0.47) | MAPTTDP1S100A4CDC25BKMT2A | |
| SCHEMBL30665385 | 0.66 | TDP2 (0.56) | TDP1S100A4CDC25BKMT2ATDP2 | |
| SCHEMBL2604368 | 0.66 | TDP2 (0.56) | TDP1S100A4CDC25BKMT2ATDP2 | |
| SCHEMBL16131492 | 0.66 | PDE10A (0.42) | MAPTTDP1S100A4CDC25BKMT2A | |
| SCHEMBL9240505 | 0.65 | RAB9A (0.44) | MAPTKMT2AMEN1GAAPDE10A | |
| SCHEMBL20851510 | 0.65 | POLB (0.36) | MAPTTDP1S100A4CDC25BKMT2A | |
| SCHEMBL29940575 | 0.64 | PDE10A (0.60) | MAPTTDP1KMT2APAX8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634445-A | Improved, cost-effective method for producing nitroxoline | 科普兰研究实验室有限公司 | 2022-06-17 | — | — | CN | disclosed |