Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879632 | 0.82 | ALDH1A1 (0.51) | PIK3CALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL2804510 | 0.81 | NPC1 (0.47) | PIK3CALMNANPSR1MEN1KMT2A | |
| SCHEMBL2856614 | 0.71 | PDE5A (0.55) | PIK3CALMNANPSR1MEN1KMT2A | |
| SCHEMBL2855842 | 0.69 | HTR2C (0.48) | PIK3CAMAPTNPC1RAB9AGGPS1 | |
| SCHEMBL2860019 | 0.67 | PIK3CA (0.58) | PIK3CALMNANPSR1MEN1KMT2A | |
| SCHEMBL2864782 | 0.66 | MEN1 (0.53) | PIK3CAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2861201 | 0.65 | PIK3CA (0.46) | PIK3CAKMT2ABRD4POLB | |
| SCHEMBL2856457 | 0.65 | PIK3CA (0.52) | PIK3CAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL3185882 | 0.65 | KDM4C (0.47) | ALDH1A1KDM4EGGPS1 | |
| SCHEMBL2807570 | 0.65 | PIK3CA (0.56) | PIK3CANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |