Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832269 | 0.82 | PIK3CA (0.46) | ALDH1A1HSD17B10TSHRGAAKDM4E | |
| SCHEMBL2856614 | 0.76 | PDE5A (0.55) | ALDH1A1TSHRKDM4EHTTMAPK1 | |
| SCHEMBL3339720 | 0.70 | KMT2A (1.00) | ALDH1A1HTTMAPK1KMT2AMEN1 | |
| SCHEMBL6792419 | 0.67 | KMT2A (0.88) | ALDH1A1GAAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL3185882 | 0.67 | KDM4C (0.47) | ALDH1A1KDM4EAURKA | |
| SCHEMBL22070916 | 0.66 | KMT2A (0.71) | ALDH1A1HSD17B10TSHRUSP2GAA | |
| SCHEMBL6237506 | 0.65 | ALDH1A1 (0.81) | ALDH1A1GAAKDM4EHTTKMT2A | |
| SCHEMBL2785338 | 0.64 | SRC (0.56) | GAAKMT2AMEN1RAB9A | |
| SCHEMBL2476165 | 0.62 | ALDH1A1 (1.00) | ALDH1A1GAAKDM4EHTTKMT2A | |
| SCHEMBL2855842 | 0.62 | HTR2C (0.48) | RAB9APIK3CAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |