Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | KDM1A | O60341 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.56 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13101601 | 0.82 | AMY1A (0.58) | RAB9AKDM1AMAPTGAAMEN1 | |
| SCHEMBL798528 | 0.81 | NPC1 (0.77) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL14422247 | 0.78 | RAB9A (0.64) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL2880884 | 0.78 | KDM1A (0.72) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL14422248 | 0.78 | NPC1 (0.60) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL789722 | 0.77 | MAPT (0.73) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL18233030 | 0.75 | L3MBTL1 (0.42) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL12268249 | 0.75 | NPC1 (0.53) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL789085 | 0.73 | NPC1 (0.98) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL14662146 | 0.73 | CTSA (0.60) | NPC1RAB9AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012793-A1 | FUNGICIDE AMINOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2010-02-04 | — | — | WO | disclosed |