Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.77 |
| ▸ | RAB9A | P51151 | 5/20 | 0.77 |
| ▸ | KDM1A | O60341 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.60 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218680 | 0.85 | KDM1A (0.56) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL798484 | 0.84 | NPC1 (0.55) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL4927035 | 0.82 | CCR4 (0.57) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL2875618 | 0.81 | NPC1 (0.70) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL789722 | 0.80 | MAPT (0.73) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL2285389 | 0.80 | AMY1A (0.60) | NPC1RAB9AKDM1ASMN1; SMN2L3MBTL1 | |
| SCHEMBL14422247 | 0.79 | RAB9A (0.64) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL789085 | 0.79 | NPC1 (0.98) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL5215470 | 0.79 | RAB9A (0.50) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 | |
| SCHEMBL5217553 | 0.78 | L3MBTL1 (0.50) | NPC1RAB9AKDM1AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037349-A2 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2010012793-A1 | FUNGICIDE AMINOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2010-02-04 | — | — | WO | disclosed |