Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.35 |
| ▸ | LPL | P06858 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762261 | 0.78 | F11 (0.39) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5149715 | 0.76 | NOTUM (0.46) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL2461405 | 0.76 | LIPG (0.40) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL484364 | 0.76 | PIK3CD (0.41) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL484221 | 0.74 | PRKCI (0.46) | CA1CA2CA9LIPGLPL | |
| SCHEMBL29807685 | 0.74 | PRKCI (0.46) | CA1CA2CA9LIPGLPL | |
| SCHEMBL28905243 | 0.74 | F11 (0.43) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL20605103 | 0.73 | KMT2A (0.48) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28877892 | 0.73 | F11 (0.41) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL16987412 | 0.73 | DGAT1 (0.38) | F11F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153643-B | Substituted indole MCL-1 inhibitors | 范德比尔特大学 | 2022-06-21 | — | — | CN | disclosed |