Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27007442 | 0.86 | DGAT1 (0.46) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL27007443 | 0.78 | SNCA (0.37) | FFAR1ROCK1IDO1TDO2DGAT1 | |
| SCHEMBL907049 | 0.75 | KDM4E (0.40) | IDO1TDO2LIPGSNCAIRAK4 | |
| SCHEMBL17437290 | 0.75 | FFAR1 (0.57) | F11FFAR1IDO1TDO2DGAT1 | |
| SCHEMBL28756734 | 0.73 | F11 (0.40) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1485295 | 0.73 | FFAR1 (0.55) | F11F2PRSS1PRSS2PRSS3 | |
| Acetic Acid SCHEMBL25322169 | 0.73 | IDO1 (0.37) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28877889 | 0.72 | S1PR1 (0.39) | F11F2PRSS1PRSS2PRSS3 | |
| Acetic Acid SCHEMBL25322175 | 0.72 | IDO1 (0.35) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL17113535 | 0.72 | IRAK4 (0.39) | FFAR1IDO1TDO2LIPGSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141202-A | Pyrimidopyrazinone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-04 | — | — | CN | disclosed |