Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091622 | 0.79 | CSNK1A1 (0.44) | CFTRPIN1NPC1 | |
| SCHEMBL996798 | 0.79 | KDM4E (0.41) | CFTRCA1BRD4HPGDSADRA2A | |
| SCHEMBL17392139 | 0.79 | ESR1 (0.50) | ESR1ESR2PIN1CDK2KMT2A | |
| SCHEMBL16423787 | 0.77 | HPGDS (0.41) | CFTRBRD4HPGDSLTA4HPIN1 | |
| SCHEMBL4904620 | 0.74 | ALDH1A1 (0.46) | CFTRBRD4HPGDSADRA2AADRA1D | |
| SCHEMBL21054194 | 0.72 | IDO1 (0.45) | CFTRBRD4HPGDSADRA1ALTA4H | |
| SCHEMBL1480019 | 0.72 | CA14 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29981780 | 0.72 | CA14 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16521356 | 0.70 | TRPA1 (0.42) | BRD4ADRA2AADRA1DADRA1AADRA1B | |
| SCHEMBL16423492 | 0.70 | HSP90AA1 (0.42) | CA1CA2BRD4ADRA2AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1809572-B | Substituted quinobenzoxazine analogs | CYLENE PHARMACEUTICALS INC | 2010-05-12 | — | — | CN | disclosed |
| CN-1809572-A | Substituted quinobenzoxazine analogs | CYLENE PHARMACEUTICALS INC (US) | 2006-07-26 | — | — | CN | disclosed |