Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353785 | 0.77 | HSD11B1 (0.41) | ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL17008352 | 0.70 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL15922930 | 0.69 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL549021 | 0.69 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL1524030 | 0.69 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL18135490 | 0.68 | HSD11B1 (0.55) | ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL5017321 | 0.67 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL29078864 | 0.67 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL13820265 | 0.67 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL4712185 | 0.65 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1898222-A | Substituted aryl cycloalkanol derivatives and methods of their use | WYETH CORP (US) | 2007-01-17 | — | — | CN | disclosed |
| CN-1897946-A | 1- 2' (1, 4'-biperidin-1'-yl)-1- (phenyl) -ethyl cyclohexanol derivatives as monoamine reuptake modulators for the treatment of visomotor symptoms | WYETH CORP (US) | 2007-01-17 | — | — | CN | disclosed |
| CN-1897950-A | Fused aryl and heteroaryl derivatives and methods of use thereof | WYETH CORP (US) | 2007-01-17 | — | — | CN | disclosed |