SCHEMBL17008352

SCHEMBL17008352

OCC1(O)C2CC3CC(C2)CC1C3

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HSD11B1 P28845 2/20 0.33
GBA1 P04062 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13820265 0.79 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2HSD11B1
SCHEMBL1524030 0.76 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2HSD11B1
SCHEMBL549021 0.76 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2HSD11B1
SCHEMBL15922930 0.76 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2HSD11B1
SCHEMBL16566251 0.75 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2
SCHEMBL14953127 0.74 HSD11B1 (0.37) ALDH1A1SMN1; SMN2HSD11B1
SCHEMBL5017321 0.74 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2HSD11B1
SCHEMBL29078864 0.74 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2HSD11B1
SCHEMBL10546677 0.73 GBA1 (0.35) GBA1GAA
SCHEMBL15923054 0.72 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220017559-A1 CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-01-20 US disclosed
US-11014955-B2 Cyclic peroxides as prodrugs for selective delivery of agents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-05-25 US disclosed
US-20200317714-A1 CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-10-08 US disclosed
US-10662215-B2 Cyclic peroxides as prodrugs for selective delivery of agents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-05-26 US disclosed
US-20190284224-A1 CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-09-19 US disclosed
US-10287312-B2 Cyclic peroxides as prodrugs for selective delivery of agents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-05-14 US disclosed
EP-3104857-A1 CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS The Regents of The University of California (US) 2016-12-21 EP disclosed
US-20160362439-A1 CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-12-15 US disclosed
WO-2015123595-A1 CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662215-B2 Cyclic peroxides as prodrugs for selective delivery of agents GPX4, PRDX1, PRDX3 ALDH1A1 135/4885SMN1; SMN2 991/4885HSD11B1 523/4885
US-11014955-B2 Cyclic peroxides as prodrugs for selective delivery of agents GPX4, PRDX1, PRDX3 ALDH1A1 135/4885SMN1; SMN2 991/4885HSD11B1 523/4885
US-20190284224-A1 CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS GPX4, PRDX1, PRDX3 ALDH1A1 135/4885SMN1; SMN2 991/4885HSD11B1 523/4885
US-20220017559-A1 CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS GPX4, PRDX1, PRDX3 ALDH1A1 135/4885SMN1; SMN2 991/4885HSD11B1 523/4885
US-20160362439-A1 CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS GPX4, PRDX1, PRDX3 ALDH1A1 135/4885SMN1; SMN2 991/4885HSD11B1 523/4885
US-10287312-B2 Cyclic peroxides as prodrugs for selective delivery of agents GPX4, PRDX1, PRDX3 ALDH1A1 135/4885SMN1; SMN2 991/4885HSD11B1 523/4885
US-20200317714-A1 CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS GPX4, PRDX1, GPX1 ALDH1A1 256/4885SMN1; SMN2 1026/4885HSD11B1 458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.