Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28762146 | 0.77 | TRPV4 (0.50) | MEN1KMT2ANPC1RAB9ACES2 | |
| SCHEMBL13714272 | 0.75 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AMAPK1POLB | |
| SCHEMBL30435123 | 0.73 | MAPK1 (0.60) | ALDH1A1MAPK1POLBCA1CA2 | |
| SCHEMBL27183074 | 0.73 | SRD5A2 (0.66) | ATMALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL11301789 | 0.73 | MAPK1 (0.60) | ALDH1A1MAPK1POLBCA1CA2 | |
| SCHEMBL11059943 | 0.72 | LMNA (0.67) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10903201 | 0.72 | MAPK1 (0.62) | ALDH1A1MEN1KMT2ARAB9AMAPK1 | |
| SCHEMBL474783 | 0.72 | MEN1 (0.60) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10373812 | 0.72 | GAA (0.62) | ALDH1A1RAB9AMAPK1POLBCA12 | |
| SCHEMBL8537295 | 0.72 | ALDH1A1 (0.62) | ALDH1A1KMT2AMAPK1POLBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502533-A | Benzenesulfonamide derivatives and use thereof | 2692372安大略公司 | 2022-05-13 | — | — | CN | disclosed |