Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922469 | 0.85 | NQO2 (0.46) | MEN1KMT2AL3MBTL1USP2POLB | |
| SCHEMBL31599989 | 0.79 | LMNA (0.40) | MEN1KMT2AL3MBTL1HTR2ANPC1 | |
| SCHEMBL31599834 | 0.76 | S100B (0.50) | MEN1KMT2AL3MBTL1NPC1CASP3 | |
| SCHEMBL22324000 | 0.75 | PDGFRB (0.46) | L3MBTL1AXLGRIN2DGRIN3BGRIN1 | |
| SCHEMBL23702268 | 0.74 | MEN1 (0.43) | MEN1KMT2AL3MBTL1AXLPOLB | |
| SCHEMBL23643801 | 0.74 | ALDH1A1 (0.42) | AXLGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28763374 | 0.74 | MAPT (0.41) | MEN1KMT2AL3MBTL1AXLGRIN2D | |
| SCHEMBL16432372 | 0.74 | AXL (0.42) | AXLGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL26655062 | 0.74 | FGFR1 (0.43) | MEN1KMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL26654804 | 0.74 | MAPT (0.41) | MEN1KMT2AL3MBTL1AXLGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111547-A1 | 2,3-DIHYDROPYROLLOPYRIDINE CARBOXAMIDE COMPOUNDS AND METHODS OF USE THEREOF | RGENTA THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| CN-110418790-B | Imidazopyrrolone compounds as p53-MDM2 inhibitors | 罗欣药业(上海)有限公司 | 2022-05-17 | — | — | CN | disclosed |