Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27687596 | 0.93 | LMNA (0.45) | TSHRGAAKDM4EPOLBALDH1A1 | |
| SCHEMBL27668652 | 0.82 | MAPK1 (0.49) | GAAKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL28765859 | 0.75 | MAPK1 (0.47) | GAAKDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL27687586 | 0.74 | KDM4E (0.42) | TSHRGAAKDM4EPOLBALDH1A1 | |
| SCHEMBL27687686 | 0.73 | AVPR2 (0.50) | KDM4EPOLBALDH1A1HTTMEN1 | |
| SCHEMBL5414838 | 0.69 | ALDH1A1 (0.59) | ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL28753498 | 0.68 | HTR2B (0.40) | GAAKDM4EHTR1AMEN1KMT2A | |
| SCHEMBL15001867 | 0.64 | SMN1; SMN2 (0.53) | TSHRGAAKDM4EPOLBALDH1A1 | |
| SCHEMBL22784252 | 0.64 | NOTUM (0.64) | TSHRGAAKDM4EPOLBALDH1A1 | |
| SCHEMBL4416703 | 0.63 | HDAC3 (0.63) | TSHRGAAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1922141-A | Novel heterocyclic compound | DAINIPPON SUMITOMO PHARMA CO (JP) | 2007-02-28 | — | — | CN | disclosed |