Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847354 | 0.86 | MMP8 (0.54) | MMP8TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL7060682 | 0.86 | MMP8 (0.56) | MMP8TDP1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL10850421 | 0.86 | MMP8 (0.48) | MMP8TDP1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL12677778 | 0.85 | TDP1 (0.55) | MMP8TDP1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL900165 | 0.85 | TDP1 (0.57) | MMP8TDP1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL7376682 | 0.84 | LMNA (0.55) | MMP8TDP1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL5321935 | 0.82 | TDP1 (0.67) | MMP8TDP1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL17783287 | 0.81 | MMP8 (0.55) | MMP8TDP1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL16587936 | 0.81 | ALDH1A1 (0.49) | TDP1L3MBTL1LMNAALDH1A1MAPK1 | |
| SCHEMBL18355825 | 0.81 | TDP1 (0.50) | MMP8TDP1L3MBTL1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103118710-A | Apoptosis imaging agents based on lantibiotic peptides | GE HEALTHCARE LTD | 2013-05-22 | — | — | CN | disclosed |
| CN-101128219-B | Improved N4 chelator conjugates | GE HEALTHCARE LTD | 2012-06-20 | — | — | CN | disclosed |
| CN-101128219-A | Improved N4 chelator conjugates | AMERSHAM HEALTH AS (GB) | 2008-02-20 | — | — | CN | disclosed |