Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28611443 | 0.74 | POLB (0.43) | ALDH1A1POLBKMT2ALMNAATM | |
| SCHEMBL28613880 | 0.71 | POLB (0.41) | SMN1; SMN2ALDH1A1POLBHSD17B10KMT2A | |
| SCHEMBL28766231 | 0.71 | POLB (0.40) | ALDH1A1POLBATMCYP1A2CYP2C9 | |
| SCHEMBL27872649 | 0.70 | PSMB11 (0.41) | TSHRALDH1A1POLBLMNAELANE | |
| SCHEMBL28766234 | 0.70 | PSMB11 (0.41) | TSHRALDH1A1POLBLMNAELANE | |
| SCHEMBL2231429 | 0.67 | ATM (0.50) | SMN1; SMN2ALDH1A1KMT2ALMNAATM | |
| SCHEMBL2777609 | 0.67 | ELANE (0.50) | ALDH1A1HSD17B10KMT2ALMNAATM | |
| SCHEMBL3876427 | 0.66 | ELANE (0.49) | ALDH1A1HSD17B10KMT2ALMNAATM | |
| SCHEMBL8958945 | 0.64 | ELANE (0.50) | ALDH1A1HSD17B10KMT2ALMNAATM | |
| Acetaldehyde SCHEMBL21059045 | 0.64 | ELANE (0.64) | ALDH1A1HSD17B10KMT2ALMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114644682-A | Preparation method of bortezomib | 海南双成药业股份有限公司 | 2022-06-21 | — | — | CN | disclosed |