Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.70 |
| ▸ | PGR | P06401 | 4/20 | 0.70 |
| ▸ | AR | P10275 | 4/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluticasone SCHEMBL4069 | 0.95 | NR3C1 (1.00) | NR3C1CYP3A4PGRARHIF1A | |
| Fluticasone SCHEMBL14135286 | 0.95 | NR3C1 (1.00) | NR3C1CYP3A4PGRARHIF1A | |
| Fluticasone SCHEMBL65401 | 0.95 | NR3C1 (1.00) | NR3C1CYP3A4PGRARHIF1A | |
| Fluticasone SCHEMBL2231799 | 0.95 | NR3C1 (1.00) | NR3C1CYP3A4PGRARHIF1A | |
| Fluticasone SCHEMBL27674669 | 0.94 | NR3C1 (0.95) | NR3C1CYP3A4PGRARHIF1A | |
| Fluticasone SCHEMBL28821706 | 0.94 | NR3C1 (0.98) | NR3C1CYP3A4PGRARHIF1A | |
| Fluticasone SCHEMBL28888601 | 0.94 | NR3C1 (0.98) | NR3C1CYP3A4PGRARHIF1A | |
| Fluticasone SCHEMBL896670 | 0.94 | NR3C1 (0.93) | NR3C1CYP3A4PGRARHIF1A | |
| Fluticasone SCHEMBL28935320 | 0.94 | NR3C1 (0.97) | NR3C1CYP3A4PGRARHIF1A | |
| Fluticasone SCHEMBL3365958 | 0.92 | NR3C1 (0.91) | NR3C1CYP3A4PGRARHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536594-A | 5-amino-2,3-dihydrothiazine-1,4-dione crystal | 麦翠奥制药公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-109071461-B | Method for preparing 5-amino-2, 3-dihydrophthalazine-1, 4-diketone crystal | 麦翠奥制药公司 | 2022-06-21 | — | — | CN | disclosed |