SCHEMBL2877019

SCHEMBL2877019

O=C(Nc1cccc2c1C(=O)c1cccc(NC(=O)c3ccccc3)c1C2=O)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 3/20 0.73
MEN1 O00255 3/20 0.66
KMT2A Q03164 3/20 0.66
MMP14 P50281 1/20 0.66
MAOA P21397 1/20 0.61
CYP1A2 P05177 2/20 0.58
TSHR P16473 1/20 0.58
NPC1 O15118 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
RAB9A P51151 1/20 0.56
CA12 O43570 1/20 0.55
CA2 P00918 1/20 0.55
CA9 Q16790 1/20 0.55
POLB P06746 2/20 0.54
MDM4 O15151 1/20 0.54
TP53 P04637 1/20 0.54
HDAC3 O15379 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30111337 1.00 CASP3 (0.73) CASP3MEN1KMT2AMMP14MAOA
SCHEMBL29607631 1.00 CASP3 (0.73) CASP3MEN1KMT2AMMP14MAOA
SCHEMBL29358319 0.98 CASP3 (0.71) CASP3MEN1KMT2AMMP14MAOA
SCHEMBL4622432 0.97 CASP3 (0.69) CASP3MEN1KMT2AMMP14MAOA
SCHEMBL9170052 0.95 CASP3 (0.68) CASP3MEN1KMT2AMMP14MAOA
SCHEMBL10705711 0.95 CASP3 (0.71) CASP3MEN1KMT2AMMP14MAOA
SCHEMBL3837625 0.92 CASP3 (0.64) CASP3MEN1KMT2AMMP14MAOA
SCHEMBL11416303 0.92 CASP3 (0.64) CASP3MEN1KMT2AMMP14MAOA
SCHEMBL12960466 0.92 MAOA (0.69) CASP3MEN1KMT2AMMP14MAOA
SCHEMBL5578376 0.91 MEN1 (0.68) CASP3MEN1KMT2AMMP14MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210308319-A1 TRANSITION TO TRANSLUCENT SUTURES UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2021-10-07 US claimed
WO-2020028666-A1 TRANSITION TO TRANSLUCENT SUTURES UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2020-02-06 WO claimed
US-20120296097-A1 PREPARATION METHOD OF ORIGINAL DYE OF VAT BROWN R XUZHOU KEDAH FINE CHEMICALS LIMITED (CN) 2012-11-22 US claimed
JP-2010508092-A 2010-03-18 JP claimed
EP-2077900-A2 METHODS AND SYSTEMS FOR IMMOBILIZING CORNEAL PROSTHESES SHIUEY, Yichieh (US) 2009-07-15 EP claimed
WO-2008103754-A2 AESTHETIC INTRAOCULAR IMPLANT TSENG JANET C (US) 2008-08-28 WO claimed
WO-2008055118-A2 METHODS AND SYSTEMS FOR IMMOBILIZING CORNEAL PROSTHESES SHIUEY YICHIEH (US) 2008-05-08 WO claimed
EP-1645296-A1 Contact lens storage-, cleaning-, and care solution, dye and method for dyeing contact lenses Kloth, Stefan (DE) 2006-04-12 EP claimed
US-5516467-A Process for producing a tinted contact lens MENICON CO., LTD. (JP) 1996-05-14 US claimed
US-4191679-A ANTHRAQUINONE DYES FUJI PHOTO FILM CO., LTD. (JP) 1980-03-04 US claimed
JP-9268168-A None JP disclosed
US-20260035564-A1 CROSSLINKABLE POLYSILOXANE COMMW SCIENT IND RES ORG (AU) 2026-02-05 US disclosed
US-12528940-B2 Crosslinkable polysiloxane COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2026-01-20 US disclosed
US-20240399110-A1 ARTICLES COMPRISING MARKINGS AND RELATED METHODS Access Vascular, Inc. (US) 2024-12-05 US disclosed
US-11992627-B2 Articles comprising markings and related methods Access Vascular, Inc. (US) 2024-05-28 US disclosed
EP-0001267-A1 Mass coloration of linear polyesters CIBA-GEIGY AG (CH) 1979-04-04 EP disclosed
US-4141881-A PERYLENE-3,4,9,10-TETRACARBOXYLIC PIGMENT MIXTURE WITH DYE CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed
US-4076736-A Preparation of aminoanthraquinones from nitroanthraquinones BAYER AKTIENGESELLSCHAFT (DT) 1978-02-28 US disclosed
US-3969302-A Process for the dyeing of colored shaped articles of high polymer, synthetic resins and preparations for such process CIBA-GEIGY AG (CH) 1976-07-13 US disclosed
US-3948828-A COLORING POLYESTERS OR POLYAMIDES CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035564-A1 CROSSLINKABLE POLYSILOXANE EPCAM, ITGB4, ITGB3 CASP3 1318/4885MEN1 4515/4885KMT2A 786/4885
US-12528940-B2 Crosslinkable polysiloxane EIF2S1, SSR4, MSR1 CASP3 4046/4885MEN1 4431/4885KMT2A 1452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.