Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 3/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28781559 | 0.78 | TLR7 (0.33) | KLK7KLK5PSEN1PSEN2APH1B | |
| SCHEMBL2578619 | 0.70 | NAAA (0.38) | LMNAKLK7KLK5PTPN1CDC25B | |
| Tert-Butyl Formate SCHEMBL27763834 | 0.65 | TDP1 (0.32) | — | |
| Tert-Butyl Formate SCHEMBL27345963 | 0.65 | IDO1 (0.61) | ALDH1A1 | |
| SCHEMBL97086 | 0.64 | TSHR (0.47) | ALDH1A1MAPT | |
| SCHEMBL19575250 | 0.63 | BCHE (0.44) | LMNABCHEACHEPSEN1PSEN2 | |
| SCHEMBL18155301 | 0.62 | MMP1 (0.37) | LMNAALDH1A1 | |
| SCHEMBL2714281 | 0.61 | TSHR (0.52) | LMNATAAR1BCHEACHECTSL | |
| Benzylamine SCHEMBL27587164 | 0.61 | LOXL2 (0.54) | TAAR1ADORA2AADORA1CYP3A4CYP2C19 | |
| SCHEMBL7280680 | 0.61 | LMNA (0.43) | LMNABCHEACHEPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101312972-B | Bicyclic cinnamide compound | EISAI R&D MAN CO LTD | 2012-06-20 | — | — | CN | disclosed |
| CN-101622258-B | Bicyclic oxomorpholine derivatives | EISAI R&D MAN CO LTD | 2012-06-13 | — | — | CN | disclosed |
| CN-101312965-B | Morpholine type cinnamamide compound | EISAI R&D MAN CO LTD | 2011-07-20 | — | — | CN | disclosed |
| CN-101622258-A | Bicyclic oxomorpholine derivatives | EISAI R&D MAN CO LTD | 2010-01-06 | — | — | CN | disclosed |
| CN-101312965-A | Morpholine type cinnamamide compound | EISAI R&D MAN CO LTD (JP) | 2008-11-26 | — | — | CN | disclosed |
| CN-101312972-A | Bicyclic cinnamide compound | EISAI R&D MAN CO LTD (JP) | 2008-11-26 | — | — | CN | disclosed |