SCHEMBL2877367

SCHEMBL2877367

CCCCCOC(=O)C(O)C(O)(CC(=O)O)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CPT2 P23786 1/20 0.51
ACLY P53396 1/20 0.51
HSPD1 P10809 1/20 0.51
BLM P54132 1/20 0.51
HSPE1 P61604 1/20 0.51
MEN1 O00255 1/20 0.40
HPGD P15428 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NAAA Q02083 1/20 0.40
HCAR2 Q8TDS4 2/20 0.39
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7860982 0.82 HSPD1 (0.56) CPT2ACLYHSPD1BLMHSPE1
SCHEMBL21248068 0.82 HSPD1 (0.60) HSPD1BLMHSPE1MEN1HPGD
SCHEMBL2463997 0.82 HSPD1 (0.68) CPT2ACLYHSPD1BLMHSPE1
SCHEMBL6288812 0.81 HSPD1 (0.71) HSPD1BLMHSPE1MEN1HPGD
SCHEMBL1218292 0.81 HSPD1 (0.71) HSPD1BLMHSPE1MEN1HPGD
SCHEMBL1659505 0.81 HSPD1 (0.51) HSPD1BLMHSPE1MEN1HPGD
SCHEMBL8567937 0.80 HSPD1 (0.50) HSPD1BLMHSPE1MEN1HPGD
SCHEMBL6050436 0.80 HSPD1 (0.57) CPT2ACLYHSPD1BLMHSPE1
SCHEMBL1038854 0.79 HSPD1 (0.53) CPT2ACLYHSPD1BLMHSPE1
SCHEMBL2877365 0.77 NAAA (0.46) MEN1HPGDRECQLKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170312200-A1 AN AGENT FOR IMPROVING MITOCHONDRIAL FUNCTION SHOWA DENKO K.K. (JP) 2017-11-02 US disclosed
EP-3213739-A1 AGENT FOR IMPROVING MITOCHONDRIAL FUNCTION AND ANTI-AGING COMPOSITION Showa Denko K.K. (JP) 2017-09-06 EP disclosed
EP-1799631-B1 HYDROXYCITRIC ACID DERIVATIVES AND SKIN EXTERNAL PREPARATIONS CONTAINING THE SAME SHOWA DENKO KK (JP) 2017-01-25 EP disclosed
US-7846970-B2 Hydroxycitric acid derivatives and skin external preparations containing the same SHOWA DENKO K.K. (JP) 2010-12-07 US disclosed
US-20070293577-A1 Hydroxycitric Acid Derivatives And Skin External Preparations Using The Same SHOWA DENKO K.K. (JP) 2007-12-20 US disclosed
EP-1799631-A1 HYDROXYCITRIC ACID DERIVATIVES AND SKIN EXTERNAL PREPARATIONS CONTAINING THE SAME Showa Denko K.K. (JP) 2007-06-27 EP disclosed
WO-2006033476-A1 HYDROXYCITRIC ACID DERIVATIVES AND SKIN EXTERNAL PREPARATIONS CONTAINING THE SAME SHOWA DENKO K.K. (JP) 2006-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170312200-A1 AN AGENT FOR IMPROVING MITOCHONDRIAL FUNCTION UQCRC1, ACAD9, CYP27B1 CPT2 102/4885ACLY 469/4885HSPD1 75/4885
US-20070293577-A1 Hydroxycitric Acid Derivatives And Skin External Preparations Using The Same HAAO, CYP8B1, CUTA CPT2 1057/4885ACLY 1171/4885HSPD1 271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.