Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | SCN1A | P35498 | 1/20 | 0.67 |
| ▸ | HTR2B | P41595 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.67 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13186317 | 0.83 | HRH3 (0.80) | HRH3MAPK1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL14287687 | 0.82 | HRH3 (0.55) | HRH3MAPK1ALDH1A1CYP1A2CHRM2 | |
| Pramoxine SCHEMBL26020 | 0.81 | ALDH1A1 (1.00) | HRH3MAPK1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL23963137 | 0.80 | HRH3 (0.67) | HRH3MAPK1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL14287625 | 0.80 | HRH3 (0.53) | HRH3MAPK1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL23804878 | 0.80 | HRH3 (0.91) | HRH3MAPK1ALDH1A1CYP1A2CHRM2 | |
| Pramoxine SCHEMBL180542 | 0.80 | LMNA (1.00) | HRH3MAPK1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL873542 | 0.79 | ALDH1A1 (0.74) | HRH3MAPK1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL10898384 | 0.79 | ALDH1A1 (0.68) | HRH3MAPK1ALDH1A1CYP1A2CHRM2 | |
| Pramoxine SCHEMBL8189224 | 0.79 | LMNA (0.80) | HRH3MAPK1ALDH1A1CYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232549-B | Compound for treating schizophrenia and application thereof | 江苏恩华药业股份有限公司 | 2022-07-12 | — | — | CN | disclosed |