Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896503 | 0.84 | EPHX2 (0.36) | ALDH1A1SMYD3NPC1 | |
| SCHEMBL8220866 | 0.75 | CA12 (0.46) | CA12CA7CA14TSHRALDH1A1 | |
| SCHEMBL27748503 | 0.75 | LTA4H (0.35) | — | |
| SCHEMBL29483621 | 0.74 | CA12 (0.54) | CA12CA7CA14TSHRALDH1A1 | |
| SCHEMBL70060 | 0.74 | KDM4E (0.54) | TSHRKDM4EHSD17B10ALOX15ALDH1A1 | |
| SCHEMBL27748375 | 0.74 | HTR2A (0.33) | — | |
| SCHEMBL28065682 | 0.73 | KDM4E (0.50) | TSHRKDM4EHSD17B10ALOX15ALDH1A1 | |
| SCHEMBL29483644 | 0.71 | TSHR (0.52) | CA12CA7CA14TSHRSMN1; SMN2 | |
| SCHEMBL27876483 | 0.68 | HRH3 (0.30) | SMN1; SMN2 | |
| SCHEMBL16057051 | 0.68 | TSHR (0.48) | CA12CA7CA14TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479274-A | Pharmaceutical compounds | HOFFMANN LA ROCHE (CH) | 2009-07-08 | — | — | CN | disclosed |