Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748503 | 0.82 | LTA4H (0.35) | HTR2AHTR2CKCNH2 | |
| SCHEMBL28823014 | 0.80 | — | — | |
| SCHEMBL28777002 | 0.74 | CA12 (0.38) | — | |
| SCHEMBL28171821 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL27896503 | 0.73 | EPHX2 (0.36) | — | |
| SCHEMBL20601948 | 0.72 | EPHX2 (0.42) | — | |
| SCHEMBL28833655 | 0.70 | HRH3 (0.40) | — | |
| SCHEMBL1516113 | 0.70 | ACHE (0.45) | — | |
| SCHEMBL27876483 | 0.70 | HRH3 (0.30) | — | |
| SCHEMBL27650078 | 0.70 | KDM4E (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922362-A | 1,3, 4-oxadiazole sulfonamide derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same | 株式会社钟根堂 | 2018-04-17 | — | — | CN | disclosed |
| CN-107567453-A | (base of indazole 4) hexahydropyrrolo and pyrrolones and application method | 艾伯维公司 | 2018-01-09 | — | — | CN | disclosed |
| CN-101479274-A | Pharmaceutical compounds | HOFFMANN LA ROCHE (CH) | 2009-07-08 | — | — | CN | disclosed |