⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739796 | 0.86 | SLC6A12 (0.60) | — | |
| SCHEMBL3742078 | 0.86 | SLC6A12 (0.60) | — | |
| SCHEMBL7739792 | 0.86 | SLC6A12 (0.60) | — | |
| SCHEMBL7740218 | 0.86 | SLC6A12 (0.60) | — | |
| SCHEMBL7740219 | 0.86 | SLC6A12 (0.60) | — | |
| SCHEMBL3109773 | 0.86 | SLC6A12 (0.60) | — | |
| SCHEMBL7410374 | 0.86 | SLC6A12 (0.60) | — | |
| SCHEMBL30445198 | 0.86 | SLC6A12 (0.60) | — | |
| SCHEMBL9278180 | 0.81 | SLC6A12 (0.57) | — | |
| SCHEMBL18585427 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151556-A | Human transferrin receptor binding peptides | JCR制药股份有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-114585637-A | MASP inhibiting compounds and uses thereof | 拜耳公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114585603-A | Prostaglandin EP4Receptor antagonist compounds | 赫普泰雅治疗有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-109790114-A | Novel chiral ligands, metallo-chelate, a variety of unnatural amino acids, the synthetic method of Malawi's promise and its key intermediate | 中国科学院上海药物研究所 | 2019-05-21 | — | — | CN | disclosed |
| CN-105377851-B | BET bromodomain inhibitors and therapeutic methods using these inhibitors | 密执安州立大学董事会 | 2018-07-20 | — | — | CN | disclosed |
| CN-104781261-B | The macrocyclic hcv inhibitors of flaviviridae | 吉利德科学公司 | 2017-08-25 | — | — | CN | disclosed |
| CN-106715418-A | Therapeutic compounds and methods of use thereof | 基因泰克公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-105377851-A | BET bromodomain inhibitors and therapeutic methods using these inhibitors | UNIV MICHIGAN REGENTS | 2016-03-02 | — | — | CN | disclosed |
| CN-104781261-A | Macrocyclic inhibitors of flaviviridae viruses | GILEAD SCIENCES INC | 2015-07-15 | — | — | CN | disclosed |