SCHEMBL7410374

SCHEMBL7410374

N[C@@H]1CCCCC1CC(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A12 P48065 5/20 0.60
SLC6A13 Q9NSD5 5/20 0.60
SLC6A11 P48066 4/20 0.60
THRB P10828 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 1/20 0.34
GABRA5 P31644 4/20 0.33
GABRB2 P47870 4/20 0.33
GABRA1 P14867 3/20 0.33
GABRR1 P24046 3/20 0.33
GABRA4 P48169 3/20 0.33
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
GRM2 Q14416 2/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
SLC6A1 P30531 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3742078 1.00 SLC6A12 (0.60) SLC6A12SLC6A13SLC6A11THRBMEN1
SCHEMBL7739792 0.95 SLC6A12 (0.60) SLC6A12SLC6A13SLC6A11THRBMEN1
SCHEMBL30445198 0.95 SLC6A12 (0.60) SLC6A12SLC6A13SLC6A11THRBMEN1
SCHEMBL7740219 0.95 SLC6A12 (0.60) SLC6A12SLC6A13SLC6A11THRBMEN1
SCHEMBL7739796 0.95 SLC6A12 (0.60) SLC6A12SLC6A13SLC6A11THRBMEN1
SCHEMBL3109773 0.95 SLC6A12 (0.60) SLC6A12SLC6A13SLC6A11THRBMEN1
SCHEMBL7740218 0.95 SLC6A12 (0.60) SLC6A12SLC6A13SLC6A11THRBMEN1
SCHEMBL28777375 0.86
Cyclohexylglycyl SCHEMBL7937138 0.83 SLC6A12 (0.43) SLC6A12SLC6A13SLC6A11ALDH1A1GRM2
SCHEMBL1925986 0.83 SLC6A12 (0.52) SLC6A12SLC6A13SLC6A11ALDH1A1GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0922054-B1 ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES GYOGYSZERKUTATO INTEZET (HU) 2002-08-14 EP disclosed
US-6121241-A TREATING CARDIOVASCULAR DISORDERS GYOGYSZERKUTATO INTEZET KFT. (HU) 2000-09-19 US disclosed
EP-0863871-B1 ANTICOAGULANT PEPTIDE ALDEHYDE DERIVATIVES GYOGYSZERKUTATO INTEZET (HU) 2000-03-08 EP disclosed
EP-0922054-A1 ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES GYOGYSZERKUTATO INTEZET KFT. (HU) 1999-06-16 EP disclosed
EP-0863871-A1 ANTICOAGULANT PEPTIDE ALDEHYDE DERIVATIVES GYOGYSZERKUTATO INTEZET KFT. (HU) 1998-09-16 EP disclosed
WO-1997046576-A1 ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES Gyógyszerkutató Intézet Kft. (HU) 1997-12-11 WO disclosed
WO-1997046523-A1 ANTICOAGULANT PEPTIDE ALDEHYDE DERIVATIVES Gyógyszerkutató Intézet Kft. (HU) 1997-12-11 WO disclosed