Formic Acid

Formic Acid

SCHEMBL28778115

C1=NNCc2ccccc21.O=CO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.35
TRPA1 O75762 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL213709 0.89 PARP1 (0.42) PARP1TRPA1
SCHEMBL29696017 0.89 PARP1 (0.42) PARP1TRPA1
SCHEMBL6488209 0.87 PARP1 (0.41) PARP1TRPA1
SCHEMBL7309901 0.81 PARP1 (0.37) PARP1TRPA1
SCHEMBL4969401 0.69 HTR2C (0.43) PARP1TRPA1
Formic Acid SCHEMBL27938520 0.69 PARP1 (0.75) PARP1
Formic Acid SCHEMBL28034893 0.68 PNMT (0.50)
SCHEMBL19540042 0.67 TSHR (0.39) TRPA1
Formic Acid SCHEMBL8436468 0.64 CYP1A2 (0.52)
SCHEMBL2940889 0.63 TRPA1 (0.44) TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101472899-A 2-substituted 4-benzylphthalazinone derivatives as histamine H1 and H3 antagonists GLAXO GROUP LTD (GB) 2009-07-01 CN disclosed