Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213709 | 1.00 | PARP1 (0.42) | PARP1TRPA1PNMTCD44MAOB | |
| SCHEMBL6488209 | 0.98 | PARP1 (0.41) | PARP1TRPA1PNMTCD44MAOB | |
| SCHEMBL7309901 | 0.92 | PARP1 (0.37) | PARP1TRPA1PNMTCD44MAOB | |
| Formic Acid SCHEMBL28778115 | 0.89 | PARP1 (0.35) | PARP1TRPA1 | |
| SCHEMBL4969401 | 0.78 | HTR2C (0.43) | PARP1TRPA1PNMTCD44MAOB | |
| SCHEMBL19540042 | 0.75 | TSHR (0.39) | TRPA1PNMTCD44MAOBHTR2C | |
| SCHEMBL5072285 | 0.71 | TRPA1 (0.44) | PARP1TRPA1PNMT | |
| SCHEMBL10152893 | 0.70 | PARP1 (0.39) | PARP1TRPA1PNMTCD44MAOB | |
| SCHEMBL28067377 | 0.69 | HTR2C (0.34) | TRPA1PNMTCD44MAOBHTR2C | |
| SCHEMBL4166260 | 0.68 | PNMT (0.37) | PNMTCD44MAOBHTR2CALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751360-A | 1-Amide-1, 2-dihydro phthalazine compound and preparation method and application thereof | 河南警察学院 | 2025-04-04 | — | — | CN | claimed |
| EP-4628483-A1 | DIHYDROPHTHALAZINE-CONTAINING COMPOUND | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2025-10-08 | — | — | EP | disclosed |
| CN-120712260-A | Compound containing dihydro phthalazine and alkenyl and its use | 正大天晴药业集团股份有限公司 | 2025-09-26 | — | — | CN | disclosed |
| WO-2025113499-A1 | COMPOUND CONTAINING HETEROCYCLIC DIHYDROPHTHALAZINE | 正大天晴药业集团股份有限公司 | 2025-06-05 | — | — | WO | disclosed |
| CN-119874617-A | Preparation method of azelastine hydrochloride intermediate | 贵州云峰药业有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-119751360-A | 1-Amide-1, 2-dihydro phthalazine compound and preparation method and application thereof | 河南警察学院 | 2025-04-04 | — | — | CN | disclosed |
| CN-119751360-A | 1-Amide-1, 2-dihydro phthalazine compound and preparation method and application thereof | 河南警察学院 | 2025-04-04 | — | — | CN | disclosed |
| CN-119751360-A | 1-Amide-1, 2-dihydro phthalazine compound and preparation method and application thereof | 河南警察学院 | 2025-04-04 | — | — | CN | disclosed |
| CN-116655591-B | 3, 4-Dihydro phthalazine-1 (2H) -ketone derivative and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-11-08 | — | — | CN | disclosed |
| CN-116655591-B | 3, 4-Dihydro phthalazine-1 (2H) -ketone derivative and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-11-08 | — | — | CN | disclosed |
| CN-117586108-A | TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof | 科罗拉多州立大学董事会法人团体 | 2024-02-23 | — | — | CN | disclosed |
| CN-117586191-A | TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof | 科罗拉多州立大学董事会法人团体 | 2024-02-23 | — | — | CN | disclosed |
| CN-111788183-B | Heterocyclic fused phenyl compounds useful for inhibiting TNIK and medical uses thereof | 韩国化学硏究院 | 2024-02-23 | — | — | CN | disclosed |
| CN-114560828-B | Polymerizable compound and optically anisotropic body formed therefrom | 江苏创拓新材料有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-111542515-B | TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof | 科罗拉多州立大学董事会法人团体 | 2023-12-05 | — | — | CN | disclosed |
| CN-116655591-A | 3, 4-dihydro phthalazine-1 (2H) -ketone derivative and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-08-29 | — | — | CN | disclosed |
| CN-116655591-A | 3, 4-dihydro phthalazine-1 (2H) -ketone derivative and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-08-29 | — | — | CN | disclosed |
| CN-113861128-B | Polymerizable compound and optically anisotropic body | 江苏创拓新材料有限公司 | 2023-08-01 | — | — | CN | disclosed |
| WO-2022138793-A1 | COMBINATION BETWEEN EP2 RECEPTOR ANTAGONIST AND IMMUNE CHECKPOINT INHIBITOR AND/OR EP4 RECEPTOR ANTAGONIST | 小野薬品工業株式会社 | 2022-06-30 | — | — | WO | disclosed |
| WO-2022138791-A1 | EP2 ANTAGONIST | 小野薬品工業株式会社 | 2022-06-30 | — | — | WO | disclosed |