Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29696017 | 0.92 | PARP1 (0.42) | PARP1TRPA1PNMTCD44MAOB | |
| SCHEMBL213709 | 0.92 | PARP1 (0.42) | PARP1TRPA1PNMTCD44MAOB | |
| SCHEMBL6488209 | 0.90 | PARP1 (0.41) | PARP1TRPA1PNMTCD44MAOB | |
| Formic Acid SCHEMBL28778115 | 0.81 | PARP1 (0.35) | PARP1TRPA1 | |
| SCHEMBL29374426 | 0.73 | PNMT (0.50) | PNMTCD44MAOBALOX15HSD17B10 | |
| SCHEMBL214465 | 0.73 | PNMT (0.50) | PNMTCD44MAOBALOX15HSD17B10 | |
| SCHEMBL4969401 | 0.72 | HTR2C (0.43) | PARP1TRPA1PNMTCD44MAOB | |
| SCHEMBL19540042 | 0.69 | TSHR (0.39) | TRPA1PNMTCD44MAOB | |
| SCHEMBL29412535 | 0.67 | PNMT (0.37) | PNMTCD44MAOBALOX15HSD17B10 | |
| SCHEMBL4166260 | 0.67 | PNMT (0.37) | PNMTCD44MAOBALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769498-A1 | Sulfonamide derivatives with elastase inhibiting activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-23 | — | — | EP | disclosed |