Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME2 | P23368 | 1/20 | 0.46 |
| ▸ | ME1 | P48163 | 1/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583921 | 0.79 | ME2 (0.48) | ME2ME1ME3GPR35POLB | |
| SCHEMBL28227062 | 0.77 | PLA2G10 (0.46) | PLA2G10PLA2G2AALDH1A1HPGDKDM4E | |
| SCHEMBL8603035 | 0.77 | ME2 (0.56) | ME2ME1ME3GPR35POLB | |
| SCHEMBL28264476 | 0.77 | ME2 (0.43) | ME2ME1ME3GPR35POLB | |
| SCHEMBL4642432 | 0.73 | HTR2A (0.56) | GPR35POLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL15621741 | 0.71 | PLA2G2A (0.50) | PLA2G10PLA2G2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL11901445 | 0.71 | PLA2G2A (0.46) | PLA2G10PLA2G2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL15090920 | 0.71 | ALDH1A1 (0.44) | ME2ME1ME3GPR35POLB | |
| SCHEMBL6583919 | 0.71 | NPC1 (0.47) | MAPTGPR55 | |
| SCHEMBL29089114 | 0.71 | PLA2G2A (0.53) | POLBPLA2G10PLA2G2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110803995-B | Method for synthesizing tertiary amine derivative through hydroboration reaction of tertiary amide under catalysis of rare earth | 温州医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-110803995-A | Method for synthesizing tertiary amine derivative by hydroboration reaction of tertiary amide under catalysis of rare earth | 温州医科大学 | 2020-02-18 | — | — | CN | disclosed |