Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 6/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368751 | 0.85 | NPC1 (0.52) | CCR3ALDH1A1SIGMAR1ACKR3 | |
| SCHEMBL27757307 | 0.85 | NPC1 (0.52) | CCR3ALDH1A1SIGMAR1ACKR3 | |
| SCHEMBL14368788 | 0.82 | ALDH1A1 (0.58) | CCR3ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL14368687 | 0.80 | EPHX2 (0.60) | CCR3HRH3ALDH1A1SIGMAR1POLB | |
| SCHEMBL14368701 | 0.80 | POLB (0.53) | CCR3HRH3ALDH1A1SIGMAR1POLB | |
| SCHEMBL27757311 | 0.80 | C3AR1 (0.50) | ALDH1A1SIGMAR1LMNA | |
| SCHEMBL14368761 | 0.80 | C3AR1 (0.50) | ALDH1A1SIGMAR1LMNA | |
| SCHEMBL28783269 | 0.78 | MCHR1 (0.52) | CCR3HRH3SIGMAR1POLB | |
| SCHEMBL14368694 | 0.78 | MCHR1 (0.52) | CCR3HRH3SIGMAR1POLB | |
| SCHEMBL5660663 | 0.77 | CCR3 (0.62) | CCR3SIGMAR1POLBACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | disclosed |