Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 14/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368761 | 1.00 | C3AR1 (0.50) | C3AR1LMNATNKS2ALDH1A1MAPT | |
| SCHEMBL27757306 | 0.90 | SIGMAR1 (0.55) | C3AR1ALDH1A1MAPTHTTSIGMAR1 | |
| SCHEMBL14368710 | 0.90 | SIGMAR1 (0.55) | C3AR1ALDH1A1MAPTHTTSIGMAR1 | |
| SCHEMBL14368751 | 0.82 | NPC1 (0.52) | ALDH1A1SIGMAR1 | |
| SCHEMBL27757307 | 0.82 | NPC1 (0.52) | ALDH1A1SIGMAR1 | |
| SCHEMBL28783269 | 0.81 | MCHR1 (0.52) | MAPTSIGMAR1 | |
| SCHEMBL14368694 | 0.81 | MCHR1 (0.52) | MAPTSIGMAR1 | |
| SCHEMBL28779126 | 0.80 | CCR3 (0.56) | LMNAALDH1A1SIGMAR1 | |
| SCHEMBL28944413 | 0.79 | EPHX2 (0.56) | ALDH1A1SIGMAR1 | |
| SCHEMBL14368746 | 0.79 | EPHX2 (0.56) | ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | disclosed |