Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27784471 | 0.95 | SLC6A3 (0.47) | SLC6A3HPGDMEN1KMT2ALMNA | |
| SCHEMBL27759418 | 0.94 | SLC6A3 (0.50) | SLC6A3HPGDMEN1KMT2ALMNA | |
| SCHEMBL27759419 | 0.89 | KMT2A (0.47) | SLC6A3HPGDMEN1KMT2ALMNA | |
| SCHEMBL31372474 | 0.84 | SLC6A3 (0.53) | SLC6A3HPGDMEN1KMT2ALMNA | |
| SCHEMBL29369652 | 0.83 | SLC6A3 (0.67) | SLC6A3HPGDMEN1KMT2ALMNA | |
| SCHEMBL27897064 | 0.77 | ALDH1A1 (0.38) | SLC6A3KMT2ALMNAHTTL3MBTL1 | |
| SCHEMBL169922 | 0.75 | MCL1 (0.49) | HPGDHTTMCL1L3MBTL1 | |
| SCHEMBL15846301 | 0.73 | SLC6A3 (0.70) | SLC6A3HPGDMEN1KMT2ALMNA | |
| SCHEMBL28077706 | 0.73 | MCL1 (0.50) | MEN1KMT2ALMNAMCL1L3MBTL1 | |
| SCHEMBL27780888 | 0.72 | ALDH1A1 (0.37) | SLC6A3MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101544526-B | Method of activating alpha position C-H key of ether compound and application thereof | RENMIN UNIVERSITY OF CHINA | 2013-03-27 | — | — | CN | disclosed |
| CN-101544526-A | Method of activating alpha position C-H key of ether compound and application thereof | RENMIN UNIVERSITY OF CHINA | 2009-09-30 | — | — | CN | disclosed |