Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287307 | 0.81 | ALDH1A1 (0.39) | ALDH1A1HPGDTSHRRAB9ANPC1 | |
| SCHEMBL287408 | 0.76 | RAB9A (0.43) | ALDH1A1HPGDTSHRRAB9ANPC1 | |
| SCHEMBL287518 | 0.75 | ALDH1A1 (0.35) | ALDH1A1HPGDTSHRRAB9ANPC1 | |
| SCHEMBL287139 | 0.73 | ALDH1A1 (0.38) | ALDH1A1HPGDTSHRRAB9ANPC1 | |
| SCHEMBL287274 | 0.72 | ALDH1A1 (0.33) | ALDH1A1HPGDTSHRRAB9ANPC1 | |
| SCHEMBL287419 | 0.72 | NPC1 (0.41) | ALDH1A1TSHRRAB9ANPC1MAPT | |
| SCHEMBL11084699 | 0.71 | ALDH1A1 (0.62) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL9717051 | 0.70 | MMP13 (0.47) | ALDH1A1HPGDTSHRRAB9AKDM4E | |
| SCHEMBL10630124 | 0.70 | NPC1 (0.64) | ALDH1A1HPGDRAB9ANPC1MAPT | |
| SCHEMBL7394648 | 0.70 | KDM4E (0.66) | ALDH1A1HPGDTSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |