Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287307 | 0.84 | ALDH1A1 (0.39) | NPC1RAB9AKMT2ASMN1; SMN2POLB | |
| SCHEMBL287408 | 0.80 | RAB9A (0.43) | NPC1RAB9AKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL287518 | 0.80 | ALDH1A1 (0.35) | NPC1RAB9AKMT2ASMN1; SMN2ESR1 | |
| SCHEMBL287274 | 0.77 | ALDH1A1 (0.33) | NPC1RAB9AKMT2ACTNNB1SMN1; SMN2 | |
| SCHEMBL287825 | 0.75 | ALDH1A1 (0.34) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL287139 | 0.74 | ALDH1A1 (0.38) | NPC1RAB9AKMT2AHSD17B10CTNNB1 | |
| SCHEMBL286788 | 0.73 | MAPT (0.35) | NPC1RAB9AKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL288004 | 0.73 | ALDH1A1 (0.48) | NPC1RAB9AKMT2ASMN1; SMN2GAA | |
| SCHEMBL287767 | 0.73 | HPGD (0.42) | NPC1RAB9AKMT2APOLBALDH1A1 | |
| SCHEMBL287813 | 0.72 | ALDH1A1 (0.45) | NPC1RAB9AKMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |