SCHEMBL28783149

SCHEMBL28783149

c1ccc(-c2c([Si](c3ccccc3)(c3ccccc3)c3ccccc3)ccc3c2Cc2ccccc2-3)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
PGR P06401 1/20 0.38
PNMT P11086 1/20 0.37
SQOR Q9Y6N5 1/20 0.37
SRD5A2 P31213 1/20 0.36
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HTR7 P34969 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28943713 0.87 SRD5A1 (0.39) SRD5A2RAB9AKDM4EALDH1A1BCHE
SCHEMBL28970858 0.79 PNMT (0.46) KDRADORA2AADORA1PGRPNMT
SCHEMBL29766669 0.79 ADORA2A (0.47) KDRADORA2AADORA1PGRPNMT
SCHEMBL150217 0.79 ADORA2A (0.47) KDRADORA2AADORA1PGRPNMT
SCHEMBL31268502 0.78 ADORA2A (0.40) KDRADORA2AADORA1PGRPNMT
Ammonia Solution, Strong SCHEMBL15283068 0.77 ADORA2A (0.46) KDRADORA2AADORA1PGRPNMT
SCHEMBL6571789 0.77 PGR (0.39) KDRADORA2AADORA1PGRPNMT
SCHEMBL5980985 0.76 PNMT (0.46) KDRADORA2AADORA1PGRPNMT
SCHEMBL30150694 0.76 ADORA2A (0.45) KDRADORA2AADORA1PGRPNMT
Ethylene SCHEMBL27775339 0.76 ADORA2A (0.45) KDRADORA2AADORA1PGRPNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110431680-B Organic electroluminescent element 保土谷化学工业株式会社 2022-07-08 CN disclosed