Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836941 | 0.78 | SIGMAR1 (0.53) | SIGMAR1FAAHPHGDHMGLLCA12 | |
| SCHEMBL11836951 | 0.78 | SIGMAR1 (0.53) | SIGMAR1FAAHPHGDHMGLLCA12 | |
| SCHEMBL23517155 | 0.78 | SIGMAR1 (0.53) | SIGMAR1FAAHPHGDHMGLLCA12 | |
| SCHEMBL966681 | 0.69 | KMT2A (0.50) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL1743264 | 0.69 | HTR3E (0.60) | SIGMAR1FAAHPHGDHMGLLCA12 | |
| SCHEMBL2232383 | 0.69 | ALDH1A1 (0.60) | SIGMAR1FAAHPHGDHMGLLCA12 | |
| SCHEMBL1630634 | 0.69 | KMT2A (0.50) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL4294754 | 0.68 | KMT2A (0.54) | MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28286729 | 0.67 | KMT2A (0.48) | FAAHPHGDHMGLLCA12CA1 | |
| Carbamic Acid SCHEMBL11482908 | 0.67 | KMT2A (0.48) | SIGMAR1FAAHPHGDHMGLLCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541742-A | Trypsin-like serine protease inhibitors, and their preparation and use | CURACYTE DISCOVERY GMBH (DE) | 2009-09-23 | — | — | CN | disclosed |