Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27784860 | 0.87 | SIGMAR1 (0.60) | SIGMAR1HPGDMEN1KMT2AMAPT | |
| SCHEMBL29063496 | 0.83 | HPGD (0.71) | HPGDMEN1KMT2AMAPTCHRM1 | |
| SCHEMBL27763342 | 0.83 | SIGMAR1 (0.55) | SIGMAR1HPGDMEN1KMT2AMAPT | |
| SCHEMBL27784859 | 0.81 | SIGMAR1 (0.53) | SIGMAR1HPGDMEN1KMT2AMAPT | |
| SCHEMBL7837595 | 0.80 | SIGMAR1 (0.68) | SIGMAR1HPGDALDH1A1POLBUSP2 | |
| Formic Acid SCHEMBL7986200 | 0.77 | SIGMAR1 (0.86) | SIGMAR1HPGDALDH1A1POLBUSP2 | |
| SCHEMBL894920 | 0.75 | SIGMAR1 (1.00) | SIGMAR1HPGDALDH1A1POLBUSP2 | |
| SCHEMBL28393 | 0.75 | SIGMAR1 (1.00) | SIGMAR1HPGDALDH1A1POLBUSP2 | |
| Hydrochloric Acid SCHEMBL1597474 | 0.74 | SIGMAR1 (0.96) | SIGMAR1HPGDALDH1A1POLBUSP2 | |
| Piperazine SCHEMBL28228981 | 0.74 | SIGMAR1 (0.96) | SIGMAR1HPGDALDH1A1POLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101591311-A | 1-(3-phenyl acryloyl) bridged piperazine derivatives and preparation method thereof | UNIV HEBEI TECHNOLOGY (CN) | 2009-12-02 | — | — | CN | claimed |
| CN-101591311-A | 1-(3-phenyl acryloyl) bridged piperazine derivatives and preparation method thereof | UNIV HEBEI TECHNOLOGY (CN) | 2009-12-02 | — | — | CN | disclosed |