Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KHK | P50053 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018338 | 0.86 | CES2 (0.56) | SIGMAR1USP2ALDH1A1CES2CES1 | |
| SCHEMBL12489727 | 0.82 | HPGD (0.62) | POLBUSP2ALDH1A1CES2CES1 | |
| SCHEMBL5564719 | 0.81 | HPGD (0.66) | POLBUSP2ALDH1A1HPGD | |
| SCHEMBL894920 | 0.81 | SIGMAR1 (1.00) | SIGMAR1POLBUSP2ALDH1A1TSHR | |
| SCHEMBL28393 | 0.81 | SIGMAR1 (1.00) | SIGMAR1POLBUSP2ALDH1A1TSHR | |
| SCHEMBL28784201 | 0.80 | SIGMAR1 (0.60) | SIGMAR1POLBUSP2ALDH1A1TSHR | |
| SCHEMBL27784860 | 0.80 | SIGMAR1 (0.60) | SIGMAR1POLBUSP2ALDH1A1TSHR | |
| Piperazine SCHEMBL28228981 | 0.79 | SIGMAR1 (0.96) | SIGMAR1POLBUSP2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL1597474 | 0.79 | SIGMAR1 (0.96) | SIGMAR1POLBUSP2ALDH1A1TSHR | |
| SCHEMBL9644712 | 0.79 | SIGMAR1 (0.96) | SIGMAR1POLBUSP2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622361-B1 | Heterocyclic compounds as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-10-04 | — | — | EP | claimed |
| US-8414982-B2 | Process for the production of strongly adherent coatings | BASF SE (DE) | 2013-04-09 | — | — | US | disclosed |
| US-8414982-B2 | Process for the production of strongly adherent coatings | BASF SE (DE) | 2013-04-09 | — | — | US | disclosed |
| EP-1836002-B1 | PROCESS FOR THE PRODUCTION OF STRONGLY ADHERENT COATINGS | BASF SE (DE) | 2012-08-29 | — | — | EP | disclosed |
| US-20090092768-A1 | Process for the Production of Strongly Adherent Coatings | CIBA SPECIALTY CHEMICALS CORP. | 2009-04-09 | — | — | US | disclosed |
| US-20090092768-A1 | Process for the Production of Strongly Adherent Coatings | CIBA SPECIALTY CHEMICALS CORP. | 2009-04-09 | — | — | US | disclosed |
| EP-0622361-B1 | Heterocyclic compounds as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-10-04 | — | — | EP | disclosed |
| EP-0657421-B1 | Hydrazine derivatives and their use as insecticides | NIHON NOHYAKU CO LTD (JP) | 1999-04-21 | — | — | EP | disclosed |
| US-5608109-A | AGRICULTURAL AND HORTICULTURAL INSECTICIDE | NIHON NOHYAKU CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0657421-A1 | Hydrazine derivatives and their use as insecticides | NIHON NOHYAKU CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |