SCHEMBL28784286

SCHEMBL28784286

COC(=O)C(=O)OC.Cc1cccc(O)c1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.68
ALDH1A1 P00352 6/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA12 O43570 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
HSD17B10 Q99714 5/20 0.47
HPGD P15428 4/20 0.47
KDM4E B2RXH2 4/20 0.47
LMNA P02545 5/20 0.47
ALOX15 P16050 2/20 0.47
CYP3A4 P08684 2/20 0.47
TP53 P04637 2/20 0.47
MAPK1 P28482 2/20 0.47
MAPT P10636 1/20 0.47
ALOX12 P18054 1/20 0.47
ATM Q13315 1/20 0.45
TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28877171 0.86 TRPA1 (0.55) TRPA1ALDH1A1CA1CA2CA12
Methoxymethane SCHEMBL27763536 0.85 TRPA1 (0.85) TRPA1ALDH1A1CA1CA2CA12
Bicarbonate SCHEMBL8910156 0.83 TRPA1 (0.81) TRPA1ALDH1A1CA1CA2CA12
SCHEMBL67369 0.82
SCHEMBL20563577 0.82 TRPA1 (1.00) TRPA1ALDH1A1CA1CA2CA12
Oxalic Acid SCHEMBL27798141 0.81 TRPA1 (0.77) TRPA1ALDH1A1CA1CA2CA12
Acetic Acid SCHEMBL4221099 0.81 TRPA1 (0.77) TRPA1ALDH1A1CA1CA2CA12
SCHEMBL27785717 0.81 TRPA1 (0.63) TRPA1ALDH1A1CA1CA2CA12
Formaldehyde SCHEMBL27890391 0.81 TRPA1 (0.85) TRPA1ALDH1A1CA1CA2HSD17B10
SCHEMBL1937642 0.80 TRPA1 (0.94) TRPA1ALDH1A1CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101544564-A Chemical synthetic method for para-methyl catechol diacetoxyl dimethyl ester HANGZHOU ZHEDA PANACO CHEMICAL 2009-09-30 CN claimed
CN-101544564-A Chemical synthetic method for para-methyl catechol diacetoxyl dimethyl ester HANGZHOU ZHEDA PANACO CHEMICAL 2009-09-30 CN disclosed