Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.62 |
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743239 | 0.88 | ACHE (0.58) | DRD2ACHESIGMAR1BACE1CNR2 | |
| Iodide SCHEMBL15145961 | 0.86 | DRD2 (0.57) | DRD2ACHESIGMAR1BACE1 | |
| SCHEMBL31596990 | 0.84 | DRD2 (0.58) | DRD2ACHESIGMAR1BACE1 | |
| SCHEMBL19734921 | 0.83 | SIGMAR1 (0.68) | DRD2SIGMAR1 | |
| SCHEMBL12501782 | 0.83 | DRD2 (0.65) | DRD2SIGMAR1DRD3 | |
| SCHEMBL9127008 | 0.83 | DRD2 (0.60) | DRD2ACHESIGMAR1BACE1 | |
| SCHEMBL4572542 | 0.82 | DRD2 (0.60) | DRD2ACHESIGMAR1BACE1 | |
| SCHEMBL8254760 | 0.81 | DRD2 (0.64) | DRD2SIGMAR1 | |
| SCHEMBL7566269 | 0.81 | DRD2 (0.63) | DRD2SIGMAR1CNR2 | |
| SCHEMBL14619656 | 0.81 | DRD2 (0.60) | DRD2SIGMAR1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101652363-A | Thiazolyl compounds as kinase inhibitor | SQUIBB BRISTOL MYERS CO US | 2010-02-17 | — | — | CN | disclosed |