SCHEMBL2878595

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2883977	0.88	SIGMAR1 (0.43)	SIGMAR1ARPTGS2ALDH1A1LMNA
	SCHEMBL2884731	0.88	SIGMAR1 (0.43)	SIGMAR1ARPTGS2ALDH1A1LMNA
	SCHEMBL2884790	0.79	SIGMAR1 (0.45)	SIGMAR1ARPTGS2ALDH1A1LMNA
	SCHEMBL2884005	0.78	TP53 (0.43)	AURKAMAPTPOLBCYP1A2CYP2D6
	SCHEMBL13051899	0.73	KCNH2 (0.42)	LMNATDP1CYP3A4ICMTKMT2A
	SCHEMBL2884324	0.72	KCNH2 (0.39)	LMNATDP1ICMTKMT2AOPRM1
	SCHEMBL2883878	0.72	KCNH2 (0.39)	LMNATDP1ICMTKMT2AOPRM1
	SCHEMBL13051900	0.72	ICMT (0.36)	LMNAMAPTICMTOPRM1GRIN1
	SCHEMBL13052090	0.72	ICMT (0.36)	LMNAMAPTICMTOPRM1GRIN1
	SCHEMBL13151807	0.69	TP53 (0.47)	ALDH1A1LMNAMAPTICMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.