SCHEMBL2883878

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13051899	0.88	KCNH2 (0.42)	KCNH2SRCTSHRTDP1ICMT
	SCHEMBL2884324	0.87	KCNH2 (0.39)	KCNH2SRCTSHRTDP1ICMT
	SCHEMBL13051900	0.86	ICMT (0.36)	KCNH2SRCICMTCNR2GRIN1
	SCHEMBL2883977	0.85	SIGMAR1 (0.43)	KCNH2SRCICMTGRIN1GRIN2B
	SCHEMBL14466311	0.81	KCNH2 (0.35)	KCNH2SRCTSHRTDP1ICMT
	SCHEMBL2886247	0.80	TP53 (0.42)	KCNH2SRCICMTCNR2MEN1
	SCHEMBL12995681	0.79	ALDH1A1 (0.42)	TDP1ICMTCNR2MEN1THRB
	SCHEMBL12995683	0.79	TP53 (0.41)	KCNH2SRCICMTCNR2MEN1
	SCHEMBL14466301	0.78	CNR2 (0.41)	TDP1CNR2GRIN1GRIN2BOPRM1
	SCHEMBL10097663	0.75	TDP1 (0.42)	KCNH2SRCTSHRTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.