SCHEMBL28786293

SCHEMBL28786293

CC(=O)CC(c1ccccc1)c1ccc2c(c1)C(c1ccc(N(C)C)cc1)CC2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
C5AR1 P21730 2/20 0.37
GPBAR1 Q8TDU6 1/20 0.36
GPR183 P32249 1/20 0.36
ADGRF1 Q5T601 1/20 0.36
GPR65 Q8IYL9 1/20 0.36
MTNR1B P49286 2/20 0.36
MTNR1A P48039 1/20 0.36
GAA P10253 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 2/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
CHRM4 P08173 2/20 0.35
DRD2 P14416 2/20 0.35
HTR7 P34969 2/20 0.35
CNR2 P34972 1/20 0.34
HCRTR1 O43613 1/20 0.34
HCRTR2 O43614 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28786292 0.82 CNR2 (0.38) ALDH1A1C5AR1GPR183ADGRF1GPR65
SCHEMBL27880552 0.77 CYP26A1 (0.39) ALDH1A1C5AR1GPR183ADGRF1GPR65
SCHEMBL8194313 0.74 ALDH1A1 (0.44) ALDH1A1GPBAR1MTNR1BMTNR1AGAA
SCHEMBL28129775 0.71 SIGMAR1 (0.55) ALDH1A1KDM4E
SCHEMBL8938880 0.68 IGF1R (0.54) ALDH1A1GAAKDM4EMAPTDRD2
SCHEMBL109205 0.66 LMNA (0.53) ALDH1A1MTNR1BMTNR1AKDM4ELMNA
SCHEMBL29067280 0.65 LMNA (0.52) ALDH1A1MTNR1BMTNR1AKDM4ELMNA
SCHEMBL30438111 0.65 LMNA (0.52) ALDH1A1MTNR1BMTNR1AKDM4ELMNA
SCHEMBL28728223 0.65 ACHE (0.35) ALDH1A1KDM4EDRD2
SCHEMBL10692480 0.64 ALDH1A1 (0.71) ALDH1A1GPBAR1GAAL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102336081-A Printing method, method for preparing overprint, method for processing laminate, light-emitting diode curable coating composition, and light-emitting diode curable ink composition FUJIFILM CORP 2012-02-01 CN disclosed
CN-101713922-A Photosensitive composition, photosensitive thin-film, photosensitive laminate material, method for forming permanent pattern and printed circuit board FUJI PHOTO FILM CO LTD 2010-05-26 CN disclosed