SCHEMBL4222599

SCHEMBL4222599

C=C(C)C(=O)OC(CC[SiH](OCC)OCC)OC(=O)C(=C)C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
TSHR P16473 3/20 0.34
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4231640 0.87 TSHR (0.37) THRBTSHRALDH1A1
SCHEMBL2878665 0.85 TSHR (0.37) THRBTSHRALDH1A1
SCHEMBL4231827 0.84 TSHR (0.41) THRBTSHRALDH1A1
SCHEMBL4222812 0.83 ALDH1A1 (0.39) THRBTSHRALDH1A1
SCHEMBL4231973 0.77 TSHR (0.34) TSHRALDH1A1
SCHEMBL142824 0.76 ALDH1A1 (0.46) THRBTSHRALDH1A1
SCHEMBL15536571 0.76 TSHR (0.40) THRBTSHR
SCHEMBL25372067 0.76 TSHR (0.36) THRBTSHRALDH1A1
SCHEMBL4196284 0.75 TSHR (0.39) THRBTSHRALDH1A1
SCHEMBL143882 0.74 THRB (0.56) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090263631-A1 FILM FORMING COMPOSITION FOR NANOIMPRINTING AND METHOD FOR PATTERN FORMATION TOKYO OHKA KOGYO CO., LTD. (JP) 2009-10-22 US disclosed