Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 8/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879426 | 1.00 | THRA (0.40) | THRATHRBSIGMAR1SPHK1TP53 | |
| SCHEMBL2878875 | 1.00 | THRA (0.40) | THRATHRBSIGMAR1SPHK1TP53 | |
| SCHEMBL2882473 | 1.00 | THRA (0.40) | THRATHRBSIGMAR1SPHK1TP53 | |
| SCHEMBL2878677 | 1.00 | THRA (0.40) | THRATHRBSIGMAR1SPHK1TP53 | |
| SCHEMBL2882385 | 0.99 | SIGMAR1 (0.40) | THRATHRBSIGMAR1SPHK1TP53 | |
| SCHEMBL2874005 | 0.95 | NPC1 (0.42) | THRATHRBSIGMAR1TP53NPC1 | |
| SCHEMBL2880337 | 0.90 | KIF11 (0.34) | SIGMAR1TP53NPC1HPGDRAB9A | |
| SCHEMBL2879761 | 0.84 | LMNA (0.35) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2875614 | 0.82 | POLB (0.36) | TP53NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL20523032 | 0.72 | THRA (0.43) | THRATHRBSPHK1TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700694-B2 | Catalyst composition and method for hydrogenating a polymer having a conjugated diene | TSRC CORPORATION (TW) | 2010-04-20 | — | — | US | disclosed |
| US-20070254802-A1 | Catalyst composition and method for hydrogenating a polymer having a conjugated diene | TSRC CORPORATION (TW) | 2007-11-01 | — | — | US | disclosed |