SCHEMBL2878725

SCHEMBL2878725

ClCC(Cl)Cc1ccccc1CC(Cl)CCl

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PNMT P11086 1/20 0.32
IDO1 P14902 1/20 0.32
ALDH1A1 P00352 1/20 0.31
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11666236 0.86 IDO1 (0.46) TSHRPNMTIDO1TAAR1
SCHEMBL8791057 0.84 TP53 (0.32) TSHRTP53TDP1
SCHEMBL8791088 0.84 HSPA5 (0.48) TSHRIDO1TAAR1AKR1B1
SCHEMBL8791083 0.84 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL6685700 0.81 CTNNB1 (0.47) TDP1ALDH1A1
SCHEMBL2875219 0.80 SLC6A2 (0.31) PNMTIDO1
SCHEMBL19987933 0.80 LMNA (0.43) TSHRTDP1ALDH1A1
SCHEMBL2880974 0.78 ALDH1A1 (0.31) ALDH1A1
SCHEMBL23456400 0.78 FOLH1 (0.49) TSHRTP53ALDH1A1
SCHEMBL6685343 0.77 EPHX1 (0.48) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100151392-A1 ANTIREFLECTIVE COATING COMPOSITIONS RAHMAN M DALIL 2010-06-17 US disclosed