SCHEMBL19987933

SCHEMBL19987933

O=Cc1ccccc1CC(Cl)CCl

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
THRB P10828 1/20 0.43
BLM P54132 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 1/20 0.36
TRIM24 O15164 1/20 0.36
TRIM33 Q9UPN9 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.32
GAA P10253 1/20 0.32
ERN1 O75460 1/20 0.31
SRC P12931 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2878725 0.80 TSHR (0.33) TDP1ALDH1A1TSHR
SCHEMBL1350340 0.76 LMNA (0.55) LMNAKMT2AMEN1THRBBLM
SCHEMBL9248722 0.75 LMNA (0.48) LMNAKMT2AMEN1THRBBLM
SCHEMBL8791083 0.75 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL548215 0.75 KMT2A (0.48) LMNAKMT2AMEN1THRBBLM
SCHEMBL10886670 0.72 LMNA (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL11666236 0.72 IDO1 (0.46) LMNATSHR
SCHEMBL548497 0.72 MEN1 (0.44) LMNAKMT2AMEN1THRBBLM
SCHEMBL2781560 0.72 SLC6A2 (0.45) LMNAKMT2AMEN1THRBBLM
SCHEMBL17103416 0.72 KMT2A (0.44) LMNAKMT2AMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559884-B2 Binder-consolidated textile fabric, method for its manufacture and its use JOHNS MANVILLE (US) 2026-02-24 US disclosed
EP-3299514-B1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE JOHNS MANVILLE EUROPE GMBH (DE) 2024-11-06 EP disclosed
CN-110835506-B Adhesive-reinforced textile fabric, method for the production thereof and use thereof 约翰斯曼维尔公司 2022-11-04 CN disclosed
CN-107869054-B Adhesive-reinforced textile, method for the production thereof and use thereof 约翰斯曼维尔欧洲有限公司 2022-05-03 CN disclosed
EP-3779015-B1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE JOHNS MANVILLE (US) 2021-12-08 EP disclosed
US-10934460-B2 Binder-consolidated textile fabrics and methods of their manufacture and use JOHNS MANVILLE (US) 2021-03-02 US disclosed
EP-3779015-A1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE Johns Manville (US) 2021-02-17 EP disclosed
CN-110835506-A Adhesive-reinforced textile fabric, method for the production thereof and use thereof 约翰斯曼维尔公司 2020-02-25 CN disclosed
US-20200056327-A1 Binder-consolidated textile fabric, method for its manufacture and its use JOHNS MANVILLE 2020-02-20 US disclosed
US-10472546-B2 Binder-consolidated textile fabrics and methods of their manufacture and use JOHNS MANVILLE (US) 2019-11-12 US disclosed
US-20180086951-A1 BINDER-CONSOLIDATED TEXTILE FABRICS AND METHODS OF THEIR MANUFACTURE AND USE JOHNS MANVILLE 2018-03-29 US disclosed
EP-3299514-A1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE Johns Manville Europe GmbH (DE) 2018-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559884-B2 Binder-consolidated textile fabric, method for its manufacture and its use SEM1, SMCHD1, SMC4 LMNA 990/4885KMT2A 1509/4885MEN1 1256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.